The 34-year-old was scheduled to join up with Oscar Tabarez’s side ahead of upcoming World Cup qualifiers against Peru, Bolivia and Ecuador.
The last of those clashes kicks off at 23:30 BST on Thursday 9 September, so Edinson would not have returned to Manchester until Friday afternoon at the earliest, with the home game against Newcastle United taking place the following day.
Uruguay is one of several South American countries currently on the UK government’s COVID-19 ‘red list’ too, meaning travelling players would have to quarantine for 10 full days upon their return, further complicating the situation.