The striker, who joined the club during last year's summer transfer window, was the clear winner in a poll on our Official App, ahead of colleagues Mason Greenwood and Victor Lindelof.
Cavani had scored seven United goals heading into the month, but caught fire in our 3-1 away victory at Tottenham, in which he scored our vital second.
He was named Man of the Match after that win, and went on to seize the award twice more (Granada, Roma) before the month was out, finishing April with a total of five goals, despite making just four starts.