The fixture will be the club's first since the departure of Ole Gunnar Solskjaer, and the difficult 4-1 defeat at Watford on Saturday that now stands as the Norwegian's final game in charge.
But there's little time to reflect on recent events for Carrick and his staff, with the Reds desperately needing a positive result in Spain.
Ahead of the match, the former United midfielder struck a positive tone and said the players were looking forward to getting on with the task at hand, despite the sadness around Ole leaving the club.
“Football's football and this is a usual day in terms of [the fact] we've got a big game to prepare for,” said Carrick, at the pre-match press conference.