The boss is not expecting Anthony Martial to be fit to face the Hammers in London after missing the last three games and forward Daniel James did not train before the FC Astana game and will be assessed tomorrow.
Rashford hasn’t scored from open play since the first match of the season, the Reds' 4-0 rout of Chelsea, with his two goals since then being a penalty in the same game and another spot-kick to win last weekend's game against Leicester City.
The 21-year-old came close to scoring at FC Astana's expense in the Europa League but couldn’t quite find the net.