The first meeting between the two clubs will kick off at 17:55 GMT as Ole Gunnar Solskjaer's side look to build on consecutive Group H victories against Paris Saint-Germain and RB Leipzig.
The players boarded an Aeroflot flight this afternoon, aiming to surge further clear at the top of the table, in advance of Leipzig's home game with PSG at 20:00 GMT.
Solskjaer had told us there was an outside chance Jesse Lingard could make the trip, but the midfielder was later not deemed ready after injury.
Alex Telles is still sidelined after testing positive for COVID-19, while fellow defenders Eric Bailly and Phil Jones are injured.