The Reds and the Gunners have a rich history in the famous competition, having met on 15 previous occasions. However, this will be our first trip to the Emirates Stadium in the FA Cup.
As we approach five years since the last goalless draw between the two sides, an exciting encounter is in prospect and a place in the fifth-round draw, which will take place on Monday night, is up for grabs.
Scroll down for our guide to the big game...
WHAT'S THE TEAM NEWS?
It remains to be seen if defenders Luke Shaw, Chris Smalling and Marcos Rojo will be available for selection.