For the third game in a row, the boss makes six changes to his starting XI, from the side that started Sunday's victory over Everton in the Premier League.
Lisandro Martinez and Kobbie Mainoo are both serving one-game suspensions for yellow cards picked up in that encounter, while Amad, Casemiro, Marcus Rashford and Joshua Zirkzee have been named among our substitutes in north London.
Andre Onana continues in goal, behind what we expect to be a back three of Noussair Mazraoui, Matthijs de Ligt and Harry Maguire - the latter returning to start for the first time since picking up a muscle injury away to Aston Villa in early October.