Manchester City travel to FC Porto looking to seal top spot in their Champions League group with one game to spare.
Pep Guardiola's side know that a point away in Portugal will be enough to seal top spot and a more favourable last-16 knockout conditions in the New Year.
It is also a big night for Inter Milan who need to beat Borussia Monchengladbach to stand any chance of reaching the knockout stages.
Elsewhere, Atletico Madrid host Bayern Munich looking to boost their hopes of reaching the last-16 stage.