Manchester City goalkeeper Ederson is absent from Pep Guardiola's squad to face Arsenal on Sunday afternoon.
He played a full part in the Citizens' victory against Club Brugge in the Champions League in midweek.
Stefan Ortega starts in his place, with veteran goalkeeper Scott Carson on the bench.
The Gunners host Manchester City at the Emirates in a resumption of what has developed into a fiery rivalry between Mikel Arteta's men and his former employers.
Ederson has made 23 appearances in all competitions for City so far this season, but has been hampered by injuries.