It’s no secret that the LSU offense will likely look pretty similar structurally to the one trotted out last year. Steve Ensminger has said so, Ed Orgeron has said so. Most of the core concepts will stay and be very very useful. I also think the run game will probably stay the same.
Unfortunately, necessity is going to dictate that some changes be made. Protections will look a bit different, the play calling sequencing will look a bit different, and there will be some new concepts. You lose a bunch of the offensive line that held strong in five-man protections; you lose the QB that was so elusive in the face of free rushers that he serves as his own sixth protector; you lose the QB who could cycle through a full five-man progression under almost any condition, and you lose two of the first round stud receivers that reliably generated separation.