LSU owns the recent rivalry with Mississippi State, winning 14 of the last 15 meetings straight up, going 11-4 against the spread in the process. However, the Tigers lost last year's meeting in Baton Rouge. LSU hopes to start another winning streak in this series when the teams meet Saturday night in Starkville.
Point spread: Tigers opened as three-point favorites, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
College football pick, via Odds Shark computer: 23.3-21.9 Bulldogs
Why the LSU Tigers can cover the spread
LSU was supposed to open its season last Saturday against McNeese State, but the game was postponed due to lightning.