Louisville has opened as a 2-point underdog for Friday night’s home game against Florida State, according to DraftKings Sportsbook. The over/under total for the game is set at 54.5.
Spreads haven’t been particularly accurate when it comes to predicting the results of U of L’s 2022 season to date. The Cards kicked off as 5.5-point road favorites against Syracuse two weeks ago, and wound up being on the wrong side of a 31-7 steamrolling. Then, last Friday, Louisville was a 5.5-point road dog against Central Florida but flew back home as owners of a 20-14 victory.