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Indianapolis Colts receiver T.Y. Hilton ruled out vs. San Francisco 49ers

Indianapolis Colts receiver T.Y. Hilton, who suffered a quad injury while making his season debut last week, has been ruled out of Sunday night's game against the San Francisco 49ers, it was announced.

Hilton, who signed a one-year contract to return to the Colts during the offseason, will now have missed six of seven games this season due to injuries.

Hilton had made his season debut against the Houston Texans before suffering the injury in the fourth quarter. After a catch, he grabbed his quad before turning upfield and trying to dive for a first down.