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Reggie Bush carted off field after slipping on concrete (The Associated Press)

ST. LOUIS (AP) -- San Francisco 49ers running back Reggie Bush has been carted off the field after slipping on concrete near the stands on a punt return.

Bush was making his first start of the season in place of the injured Carlos Hyde. The 49ers' Twitter account said Bush is questionable to return because of a knee injury.

Bush entered Sunday's game against the St. Louis Rams with just eight carries for 28 yards and a long gain of 9 yards.

Hyde was ruled out earlier in the week with a foot injury.