The Arizona Cardinals (1-2) have gotten off to a rough start in 2016 and hope to bounce back from a 33-18 road loss to the Buffalo Bills last week as 4.5-point favorites. In Week 4, they'll host the Los Angeles Rams (2-1) on Sunday as large home chalk.
The Rams have won their last two games, including a surprising 37-32 road victory against the Tampa Bay Buccaneers as 3.5-point underdogs.
Point spread: The Cardinals opened as 8.5-point favorites, with the total at 44, according to sportsbooks monitored by Odds Shark (line updates and matchup report).