The San Francisco 49ers beat the Los Angeles Rams 24-9 on Monday Night Football in the final game of Week 4, and Peyton and Eli were on the ManningCast to break down the action.
These two teams last met in January's NFC title game, where the 49ers fell 20-17 to the eventual Super Bowl champs. Despite that victory, the team has struggled in recent years against San Francisco. The Rams have recorded seven consecutive regular-season losses against the 49ers -- and five of those have been decided by one score.
Peyton and Eli welcomed Philadelphia Eagles QB Jalen Hurts, Golden State Warriors star Stephen Curry and Emmy Award-winning actor Jon Hamm for this NFC West showdown.