Jason Castro hit a walk-off home run into the waiting arms of an eager fan in the Crawford Boxes in left field, sending the Dodgers to a painful 3-2 loss in 10 innings and a three-game weekend sweep at Minute Maid Park in Houston.
The Dodgers have lost five straight games for the first time since May 1-10, 2013.
Chris Hatcher struck out the first batter he faced in the 10th inning, his 11th straight batter retired since returning from the disabled list. Then came Castro, who hit his 11th home run of the season.