Andre Everett Ethier was born on April 10th, 1982, in Phoenix, Arizona. He is one of seven children. He has three brothers, Adam, Devon and Steven, and three sisters, Catherine, Belinda, and Shaye. His father, Byron, has Cherokee and French-Canadian ancestry. His mother, Pricilla, is Mexican American.
His father played ball under Gary Ward at Yavapai Junior College and was part of the JC National title winning team. His grandfather, Pierre, Pete, Ethier, played professional baseball at the minor league level reaching AAA. One of his brothers, Devin, also played baseball and was drafted by the Dodgers in the 32nd round in 2010.