Prior to Major League Baseball settling on a dramatically shortened 2020 Draft, the Houston Astros had been stripped of their top two picks this year and in 2021 as part of the punishment levied for their electron sign-stealing.
Including a compensation pick received when Gerrit Cole signed with the New York Yankees, the Astros still had four selections in the 2020 MLB Draft. Their first (No. 72 overall) was used on right-handed pitcher Alex Santos out of Mount Saint Michael Academy in New York.
Then in the third round, Houston drafted Vanderbilt right-handed pitcher Tyler Brown with the 101st overall pick.