Michael Ezeike began his journey to the NFL as a star for Colony High School in Ontario, California. He earned a four-star rating by 247 Sports and was the 39th-ranked prospect in the state by ESPN.com. As a senior, Ezeike caught 50 passes for 960 yards and a whopping 15 touchdowns. The prior, he recorded 740 yards and 10 scores as junior.
Ezeike decided to take his talents to nearby UCLA where he immediately saw time on the field with a pair of starts and playing in 10 games total as a true freshman.