One change for Ohtani will be at catcher, where Rene Rivera is scheduled to start for Martin Maldonado, who was placed on the bereavement list Friday.
"Rene will pick up right where Maldy left," manager Mike Scioscia said. "Rene understands his pitches, understands what he's doing with the hitters. Hopefully it will be a seamless transition."
The occasion, as historic as it is, happens once in awhile, not once in a lifetime.
In fact, Albert Pujols is the fourth player in as many years and the ninth since 2000 to reach the 3,000-hit plateau.
Friday wasn't even the first time that the Angels' Ian Kinsler and Chris Young shared the same field for such a moment.