It was notable for how challenging it was.
Mayers was drafted by the St. Louis Cardinals in 2013. He had a progressing minor league career before being called up to the big club in 2016. The Cardinals called Mayers up because they needed a fill-in start in a second game of a double header against the Los Angeles Dodgers.
While growing up in Grove City, Ohio, Mayers dreamed of his Major League debut. No doubt he imagined winning the game while striking out the side with the bases loaded. His teammates surrounding him and congratulating him on a job well done.