Goals from Raul Jimenez and Ruben Neves knocked the Reds out in the third round on a night when Divock Origi briefly brought the visitors level and Xherdan Shaqiri later struck the woodwork.
Klopp had made nine changes to his starting XI – and was forced into another on six minutes, with 16-year-old Ki-Jana Hoever replacing the injured Dejan Lovren – and detailed why they were necessary during his post-match press conference.
He also reflected on the efforts of youngsters Rafael Camacho and Curtis Jones, who each made their senior debuts for the club, and more.