Wolves could give a debut to Brazilian midfielder Joao Gomes, who was linked with a move to Liverpool before arriving at Molineux.
Liverpool's Ibrahima Konate is out with a muscle injury, joining usual centre-back partner Virgil van Dijk on the sidelines.
Diogo Jota is nearing a return to full training but remains out along with Roberto Firmino and Luis Diaz.
CHRIS SUTTON'S PREDICTION
Liverpool did beat Wolves in the FA Cup last month, but only after a replay when a VAR error saved their bacon late in the first game.
Both teams made lots of changes too, so it is hard to read too much into what happened in either game when it comes to calling this one.