Neil Critchley's U23s host Sparta Prague at Prenton Park in the Premier League International Cup on Tuesday November 28, with kick-off set for 7pm GMT.
The young Reds then face Stoke City in the U23 Premier League Cup at the Swansway Chester Stadium, home of Chester FC, on Sunday December 3 at 1pm.
On the European stage, the U19s – led by Reds legend Steven Gerrard – take on Spartak Moscow in the final UEFA Youth League group game at Prenton Park on Wednesday December 6 at 12.30pm. The young Reds have qualified for the last 16 of the competition and will want to sign off their group in style with a win.