The Reds beat Les Parisiens 3-2 at Anfield in a thrilling encounter in September and handed Thomas Tuchel's side what remains their only defeat of the season across all competitions.
The reigning French champions made it 14 wins out of 14 in Ligue 1 on Saturday as they beat Toulouse 1-0.
PSG were without injured star duo Neymar and Kylian Mbappe, but Tuchel has confirmed both will feature against the Reds at the Parc des Princes.
A repeat victory for Liverpool would see them secure progress to the Champions League knockout stages with a game to spare, should Red Star Belgrade fail to beat Napoli in Italy on the same matchday.