With Manchester City not in action until Sunday, Jürgen Klopp's Reds can leapfrog the leaders with victory at Anfield and go two points clear.
Opponents Huddersfield head into the match off the back of a 2-1 defeat by Watford and cut adrift at the foot of the table with 14 points.
New manager Jan Siewert arrived from Borussia Dortmund to replace David Wagner in January - so, what can we expect from his Terriers side on Friday?
We caught up with chair of the Huddersfield Town Supporters' Association and Ooh To Be A... podcast host Jim Chisem (@jim_chisem) to get the lowdown.