Alexis Mac Allister is fit to play despite missing Liverpool's FA Cup win against Norwich as a precaution.
This game comes too soon for Thiago Alcantara, who has resumed training following a long-term hip issue.
Mohamed Salah, Kostas Tsimikas, Joel Matip, Stefan Bajcetic and Wataru Endo also remain unavailable.
Chelsea defender Levi Colwill is ruled out by a minor injury sustained whilst warming up before Friday's FA Cup game against Aston Villa.
Christopher Nkunku and Malo Gusto are back in contention, while head coach Mauricio Pochettino has said Nicolas Jackson could be involved if he returns in time following Senegal's Africa Cup of Nations elimination.