The Japan international bagged a brace in the 3-0 third-round win at Norwich City and could therefore become the first Reds player to net at least twice in consecutive rounds of the competition since Fowler in 1996.
Overall, Minamino has scored four times in three League Cup appearances for the club.
For more pre-match facts and figures from LFC statistician Ged Rea, read on…
This will be the 70th meeting between Liverpool and Preston and the first since January 2009, when Albert Riera and Fernando Torres scored in a 2-0 FA Cup third-round victory at Deepdale
Conor Bradley, Kaide Gordon and Tyler Morton all made their senior debuts at Carrow Road in the last round, while Ibrahima Konate also made his first appearance in this competition
In 19 League Cup ties under Jürgen Klopp, 73 different players have been used
Liverpool have scored 41 goals in 13 matches across all competitions this season, with 30 coming in eight away games
Klopp’s side have netted in each of their last 22 away fixtures in all competitions and have scored three or more in nine successive away league and cup matches
Divock Origi’s next League Cup goal will see him move alongside Danny Murphy into joint-sixth on the club’s all-time scorers list in this competition – the Belgian has scored 10 times in 14 ties for the Reds so far