Should Liverpool's No.11 net at The Hawthorns, he will equal the highest number of goals scored in a 38-game Premier League season (31) - a total only previously achieved by Suarez, Ronaldo and Shearer.
Read on for seven more fascinating pre-match facts, courtesy of club statistician Ged Rea...
Salah's next top-flight goal in 2017-18 will also see him draw level with Roger Hunt as only the second player in Liverpool's history to score in 23 league games in a single campaign (Hunt did so in the Second Division in 1961-62).
Roberto Firmino, meanwhile, is two goals short of registering 50 for Liverpool in all competitions.