The Reds and the Terriers are locked together on 26 league wins apiece after Klopp's side's 3-0 Premier League victory at Anfield earlier this season.
For all your need-to-know pre-match facts and figures, courtesy of club statistician Ged Rea, read on...
Liverpool are unbeaten in the last 10 league meetings with Huddersfield home and away, winning seven and drawing three.
The last league meeting between the teams in Yorkshire came at Leeds Road in February 1972, with a Jack Whitham goal earning the Reds a 1-0 victory.
Liverpool have outscored the Terriers 116-113 in the 68 league clashes between the clubs.