The Reds must overcome a 3-0 deficit in the second leg of the Champions League last-four tie following last week's result at Camp Nou.
The club have hosted 18 European semi-finals in the past, winning 14, drawing three and losing just once.
For more need-to-know pre-match facts and figures, courtesy of club statistician Ged Rea, read on...
This is Liverpool's 19th European semi-final and their 11th in the major competition. They aim to reach their 14th European final and their ninth in the European Cup.
The Reds have won three of their four European semi-finals against Spanish opposition.