Jürgen Klopp's men are currently on the club's best run in the competition since August 2009 when they went 31 games without defeat at Anfield.
The Reds last faced Cardiff in the top flight at L4 during the 2013-14 season, when they won 3-1. A 6-3 triumph in South Wales would follow later in the campaign.
For more need-to-know pre-match facts and figures, courtesy of club statistician Ged Rea, read on...
There have been 15 previous league and cup encounters with Cardiff at Anfield and there has yet to be a draw.