The feat was last achieved by Rafa Benitez's Reds in 2008-09 - that being just the 10th time in the club's history such a run had been put together.
A point against the Seagulls would also almost certainly be enough for Jürgen Klopp's Liverpool to secure a top-four Premier League finish a place in the Champions League next term.
For more need-to-know pre-match facts and figures, courtesy of club statistician Ged Rea, read on...
This will be Liverpool's 1,000th Premier League game in total and 500th at home.
The last time Brighton faced the Reds in the league at Anfield was in 1982, when they lost 3-1.