Match information
The game will be held at St Mary's with kick-off at 3pm BST.
How to follow
Listen to live commentary on the full 90 minutes here on Liverpoolfc.com. Steve Hunter and Nigel Spackman will call the action as it happens.
Get post-match reaction on LFCTV GO after the full-time whistle, with short match highlights available from 7pm BST.
Extended highlights will be published at midnight. Join LFCTV GO now and claim your first month for free.
The last meeting
A frantic Friday night contest between the sides in April saw title-chasing Liverpool emerge 3-1 winners.