Jayden Bogle and Chris Basham are the latest Sheffield United players to suffer injuries.
The pair have been ruled out for the next few weeks and join John Egan, Jack O'Connell, Sander Berge, Jack Robinson and Lys Mousset on the sidelines.
Liverpool captain Jordan Henderson is not expected to be fit until at least April following groin surgery.
Fit-again forward Diogo Jota could be involved, while Fabinho and James Milner return to training on Saturday,
A decision on goalkeeper Alisson's availability is yet to be made after his father passed away earlier this week.
LAWRO'S PREDICTION
Where do you start with Liverpool?