Liverpool put five past Roma at Anfield, but it could be a lot different at the Stadio Olimpico.
On their own turf the Italian side are yet to concede a goal in the Champions League and they have come up against some impressive opposition in the capital.
They kept Antoine Griezmann and Atletico quiet in the group stage and did the same to Chelsea and Qarabag before keeping out Shakhtar in the last 16 and a Barcelona team containing Lionel Messi and Luis Suarez.
Eusebio Di Francesco’s side have kept clean sheets in the second leg of the previous two rounds to progress on away goals.