Liverpool U23s will begin the 2019-20 Premier League 2 season at home to Tottenham Hotspur on Saturday August 10.
The game will be played at the Academy, with kick-off scheduled for 2pm BST.
The first mini-derby of the season against Everton is set for Sunday November 3, while the young Reds are set to conclude their PL2 campaign at home to Leicester City in May.
As well as competing in PL2, Neil Critchley's side will also take part in the EFL Trophy - which is at U21 level - the Premier League International Cup and Premier League Cup, with full details of those fixtures to follow on Liverpoolfc.