The match will kick off at 3pm on Wednesday, October 2, before the senior sides battle it out at Anfield later in the evening at 8pm.
Barry Lewtas’ side began their campaign with a deserved 1-1 draw in Napoli earlier this month, substitute Layton Stewart grabbing an equaliser after Andrea Mancino's first-half strike.
Salzburg also began their campaign with a 1-1 draw in their home game against Genk on matchday one.
The UEFA Youth League group mirrors that of the senior side with the top two in each group qualifying for the last 16.
Tickets are on sale now priced £3 for adults and £1 for juniors and concessions.