The game against the Hammers at Anfield will be the Reds' 40th of the campaign and if Jürgen Klopp's side score in any of their next five outings, they will reach the century mark in the third-fewest number of matches in the club's history.
Liverpool have netted 100 times in a season on 23 previous occasions, the most recent of those being 2013-14.
For all your need-to-know pre-match facts and figures, courtesy of club statistician Ged Rea, read on...
Liverpool have scored at least twice in 12 of their last 13 games in all competitions.