The Reds head to Estadio do Dragao with a 2-0 advantage from their quarter-final first leg at Anfield and have not lost in seven meetings with the Portuguese outfit.
Liverpool have won four and drawn three of their clashes with Os Dragoes in all competitions and ran out 5-0 winners in Porto when they met in the last 16 of the Champions League last season.
For more need-to-know pre-match facts and figures, courtesy of club statistician Ged Rea, read on...
Liverpool have won 10 of their previous 14 European Cup quarter-finals, including four of the last five.