Kick-off is at 7pm GMT and the official matchday programme will keep you informed and entertained with all the latest Reds news.
Inside, there are exclusive interviews with striker Courtney Sweetman-Kirk, who has now experienced the Merseyside derby in both red and blue, and midfielder Rhiannon Roberts, and we also introduce a key member of the Reds' backroom staff, physio Hina Chauhan.
Manager Vicky Jepson offers her thoughts going into the game while we also hear from captain Sophie Bradley-Auckland.
We also have the lowdown on our local rivals as well as all the latest match action, facts and statistics.