The Reds will kick off their Group D campaign with a trip to AFC Ajax before hosting FC Midtjylland.
Back-to-back meetings with Atalanta BC will then be played either side of the November international break.
After welcoming Ajax to Anfield, Jürgen Klopp’s side will complete the section at Midtjylland.
Liverpool’s Champions League Group D fixture list
October 21 (8pm) – Ajax (A)
October 27 (8pm) – Midtjylland (H)
November 3 (8pm) – Atalanta (A)
November 25 (8pm) – Atalanta (H)
December 1 (8pm) – Ajax (H)
December 9 (5.