The Reds have won six of the previous seven meetings between the clubs, and nine of the last 11.
Last season’s fixtures saw the Hornets claim a 3-0 victory at Vicarage Road in December, before Joe Allen and Roberto Firmino scored to give Liverpool a 2-0 win at Anfield in May.
The Reds’ biggest league victory over Watford came at Anfield in November 1987, when they won 4-0 thanks to second-half goals from Steve McMahon, Ray Houghton, John Aldridge and John Barnes.
In 18 previous league matches between Liverpool and Watford, there has never been a goalless draw.