Liverpool midfielder Curtis Jones is available for the first time since being injured in February.
Andy Robertson could also return after missing out against Brighton but Wataru Endo is a doubt after sustaining a knock last weekend.
Sheffield United will be without George Baldock and Tom Davies for up to six weeks.
Striker Cameron Archer, currently recovering from a calf injury, should feature again this season.
MATCH FACTS
Head-to-head
- Liverpool have won their last six league meetings, conceding only once.
- Sheffield United's last league victory against Liverpool came at Anfield in April 1994.