Liverpool's Joel Matip is close to full fitness but will be assessed before a decision is made if he can feature.
Manchester United boss Ole Gunnar Solskjaer has definitely ruled out Phil Jones and Brandon Williams.
Aside from them, he says he will give "everyone a chance" to prove their fitness - including Anthony Martial, Nemanja Matic and Victor Lindelof.
MOTD COMMENTATOR'S NOTES
Guy Mowbray: Liverpool's 2-0 win against United in this fixture last season gave them a THIRTY-point lead over their great rivals. Now, two days short of a year later, the champions need a win just to draw level on points with them.