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Liverpool are without Adam Lallana for the 228th Merseyside derby because of a thigh problem sustained playing for England earlier this week.
Jordan Henderson and Daniel Sturridge remain out, but Philippe Coutinho and Roberto Firmino are in contention.
Everton's Seamus Coleman is sidelined for the season with a broken leg, while Ramiro Funes Mori has a knee injury and also faces a lengthy spell out.
Midfielders Morgan Schneiderlin and James McCarthy are also unavailable.
MOTD COMMENTATOR'S NOTES
Guy Mowbray: "Does form go out of the window for derbies?