Liverpool defenders Trent Alexander-Arnold and Joel Matip are expected to be out for between two and three weeks through injury.
Alexander-Arnold has an ankle injury and Matip a calf issue - both came off during the game at Arsenal on Sunday.
It is a further blow for the Reds after winger Luis Diaz was ruled out with a knee injury - also picked up against Arsenal - until December.
Liverpool lost 3-2 to the Premier League leaders at Emirates Stadium.
The result leaves the Reds in 10th place, 14 points off the top after winning just two of their opening eight Premier League matches.