Football's world governing body FIFA has announced that the Reds will begin their campaign at the 40,000-capacity Education City Stadium in Doha in a semi-final on December 18.
Win or lose, they will play in the same venue which will host the third-place play-off and the final on December 21.
Jurgen Klopp's Champions League winners could face local side Al Sadd, coached by former Barcelona midfielder Xavi, Hienghene Sport of New Caledonia or most likely Mexican side Monterrey in the semi-final.
Qatar is using the 2019 and 2020 Club World Cup tournaments as a testing ground for its hosting of the 2022 World Cup finals.