Liverpool's Brazilian duo Alisson Becker and Fabinho will travel directly to Spain from international duty to complete their Covid-19 quarantine.
The club are sending them to Madrid, where Liverpool face Atletico Madrid in the Champions League on Tuesday, to finish their 10 days in isolation.
Liverpool hope they will be able to face Atletico, before they return to the UK after the rest of the team.
Brazil have just played World Cup qualifiers in Colombia and Venezuela.
Both of those countries are on the UK's red list.
"We had to sort quarantine issues and the decision we made is the boys will not be here [Liverpool]," said Reds boss Jurgen Klopp.